Daniel Holz is a professor at the University of Chicago in the Departments of Physics, Astronomy & Astrophysics, the Enrico Fermi Institute, and the Kavli Institute for Cosmological Physics.

Holz is a member of the Laser Interferometer Gravitational-Wave Observatory (LIGO) collaboration; his research focuses on black holes, gravitational waves, and cosmology. He has received a National Science Foundation CAREER Award, a Quantrell Award for Excellence in Undergraduate Teaching, and as a member of LIGO received the Breakthrough Prize in Fundamental Physics and the Gruber Prize. He was selected as a Kavli Fellow of the National Academy of Sciences and is an APS Fellow.

Holz is Chair of the Science and Security Board of the Bulletin of the Atomic Scientists, and in this role helps set the time of the Doomsday Clock. Holz is also founding director of the UChicago Existential Risk Laboratory (XLab), an interdisciplinary effort focused on understanding and mitigating existential risks, including nuclear war, climate change, and AI-fueled disinformation.